Avoid tackles
Rapidly tap [B] and it will be harder to tackle you.
4th down play
If you just did a play and realize that it is 4th down, do not use a timeout and do a field goal or punt. Press [Select] and do a Hail Mary. If your team is average, you catch it 90% of the time.
Getting away from the opposition
Zig zag very fast to get away from the opposing team.
Field goal block
Use the field goal block on the 1st, 2nd, and 3rd down to stop the opposing in their tracks.