Afro Samurai Cheats - PlayStation 3
Beat the game once on story mode to unlock hard mode and treasure viewer.
You will know that he is about to do a big attack when his weapon sparkles. Time your blocks to parry his attacks. When he is open use any desired combo until he backflips away. Repeat this until he has been defeated.
Defeating Brother 6 (with Flamethrower)
Start by either running a circle around him until he stops shooting fire or hit you with the fire. If he hits you, he will laugh and give you an opportunity to attack. Use the [Square] Slash to stun him. Next, use the [Square]x4 combo until he shoves you away. After hitting the ground, immediately use the [Square] Slash. If done fast enough, you will interrupt his attack and stun him. Repeat the combo on him, then repeat the entire process through all of the phases.