Master code
Enter "LEANEST" as a code to unlock all cheats.
Level select
Enter "MME_WEB" or "MIME_WEB" as a code to unlock the level select option on the specials menu. Note: "_" indicates a space.
Full health
Enter "WEAKNESS" as a code.
Big head mode
Enter "EGOTRIP" as a code.
Comic collection
Enter "FANBOY" as a code.
All FMV sequences
Enter "CINEMA" as a code.
All gallery characters
Enter "RGSGLLRY" as a code.
What If Contest mode
Enter "UATUSEES" as a code. In this mode, the game will be subtlety changed from level 2 onward.
Cartoon Spider-Man
Enter "FUNKYTWN" as a code.
Spidey 2099 costume
Enter "MIGUELOH" as a code. This costume allows Spider-Man to do double damage. Alternately, collect all comics in the game.
Captain Universe costume
Enter "TRISNTNL" as a code. This costume allows Spider-Man to have double damage, unlimited webbing, and invincibility. Note: "_" represents a space. Alternately, successfully complete the game under the hard difficulty setting.
Spidey Unlimited costume
Enter "SYNOPTIC" as a code. This costume allows Spider-Man to have stealth mode by pressing L. Alternately, successfully complete the game twice in a row under the same difficulty setting and using the same costume.
Amazing Bagman costume
Enter "KICK_ME" as a code. Note: "_" represents a space.
Ben Reilly costume
Enter "CLUBNOIR" as a code. Alternately, successfully complete level 4-2.